It is important you know your blood type and genotype to avoid hemolytic anemia and other blood-related diseases .
This article will guide you on the list of genotypes and their blood group compatibles.
But before diving into which genotypes are compatible, it is important that you first understand genotype definition.
What is Genotype?
A genotype is the genetic composition of an organism. It is the sum of all the traits/genes you inherited from your parents. They are localized inside the chromosome of the nucleus.Types of Genotype in Humans
There are six types of genotype in existence and every human being carries a pair of hemoglobins. They are distinguished by the alleles they carry. The list of genotypes is as follows.
Genotype: AA
AS genotype
Genotype: AC
SS Genotype
Genotype: SC
Genotype: CC
SS genotype and AC are the abnormal genotypes that cause sickle cell anemia or thalassemia diseases.
Blood Group and Genotype Compatibles
The human blood group, also known as blood types, is classified based on the presence and absence of antigens on the surface of red blood cells. These antigens may be carbohydrates, proteins or glycoproteins.
According to a recent study , 36 human blood groups have been recognized by the International Society of Blood Transfusion. However, only the ABO group and the rhesus factor are considered because of their importance in blood transfusion and in preventing
blood-related diseases.
The ABO blood group is classified based on the antigens on their surface. For instance,
Blood type A has antigen A on the surface of the blood
Type B has antigen B on the surface of the blood
Blood type AB has both antigen A and B on the surface of the blood
Type O has neither A nor B on the surface of the blood.
Blood donor/recipient compatibility
Those with blood group O are universal donors, meaning that they can donate blood to all the blood groups
AB+ are universal blood recipients, they can receive blood from all blood groups.
AB- can receive blood from those with A-, B-, AB- and O-
A+ can receive blood from A+, O+, A- and O-
B+ can receive blood from those with B+, O+, B- and O
B- can receive blood from only two groups: B- and O
O+ can receive blood from those with O- and O+ blood groups
O- can only receive blood from O.
summary of the blood types and their genotype, antigen, and antibody.
blood group and genotype compatible
Blood type A has genotype AA or AO, antigen A in red blood cells and antibody B in plasma cells.Blood group B has BB or BO genotype, antigen B in the red blood cells and An antibody in the plasma.AB blood group has AB genotype, antigen A and B and no antibodies.
O blood group has an OO genotype, no antigens but has A and B antibodies in the plasma
.
❤. What is the Rhesus Factor’Rh’
The rhesus factor (Rh) is an inherited protein substance found on the surface of red blood cells. Those that have the protein on the surface of their blood are Rh positive, while those without the protein are Rh negative.Rh-positive is more common than Rh- and is never a sickness if you are Rh-positive or negative. However, a problem arises when the Rh of the mother differs from that of her baby (Rh incompatibility).If maybe during delivery or you experienced bleeding during pregnancy and your blood came in contact with that of your baby, your body would produce Rh antibodies.
❤. These antibodies will not cause any problems in your first pregnancy but can affect your subsequent pregnancies if you and your baby’s Rh factor is incompatible.
Rh antibodies may cross the placenta and damage the red blood cells of the baby, causing a life-threatening anemia.
It is always advisable for pregnant mothers to register for antenatal so they will check the Rh status of their unborn baby for compatibility.If their Rh is different, an Rh immune globulin injection will be given to the woman before delivery, to prevent her body from producing Rh antibodies. ( 4 )
How to Know Your Genotype Without a Blood Test
❤. The only reliable way to know your genotype without a blood test is when both of your parents are AA, then your own genotype will be AA.
However, it is always advisable to go for your own genotype testing in at least two different hospitals to be sure of your results.
Which blood group and genotype are the best
❤.Except for the SS and AC genotype that causes thalassemia disease or blood-related sickness, all the other genotypes are good. They have both advantages and disadvantages, for example, someone with genotype AA can marry anybody even someone with SS genotype, but they are more prone to malaria sickness.Someone with AS genotype cannot marry SS or AC, but their blood is more resistant to malaria. So, all the blood types and genotypes are good provided they are compatible.Genotype vs phenotype, what is the difference?
❤. As I earlier said, the genotype of an organism is the set of genes or characters it carries. It is inherited from their parents. Examples of genotype are the genes responsible for all these characters
Eye Colour
hair colour
height
certain behaviors
the size of a bird’s beak
the length of a fox’s tail
the colour of stripe. s on a cat
certain diseases
how your voice sounds.
❤ A phenotype is the physical appearance of an organism.It is influenced by the genotype and the environment the organism lives in. Their examples are
Eye colour
skin colour
Certain types of disease
Hair colour
Height
The sound of your voice
Size of a bird’s beak
The colour of the stripes on a cat ( 5 )
Bottom line
Sickle cell anemia is real, intending couples should always go for a genotype test to confirm their blood group compatibility before getting married. Help us reduce the level of blood-related diseases today. Always remember that prevention is far better than cure.
No comments:
Post a Comment